<b>LARGE GRANULAR LYMPHOCYTES AND KUPFFER CELLS IN REGENERATING RAT </b><b>LIVER </b>
نویسندگان
چکیده
منابع مشابه
Iron activates NF- B in Kupffer cells
She, Hongyun, Shigang Xiong, Min Lin, Ebrahim Zandi, Cecilia Giulivi, and Hidekazu Tsukamoto. Iron activates NFB in Kupffer cells. Am J Physiol Gastrointest Liver Physiol 283: G719–G726, 2002; 10.1152/ajpgi.00108. 2002.— Iron exacerbates various types of liver injury in which nuclear factor (NF)B-driven genes are implicated. This study tested a hypothesis that iron directly elicits the signalin...
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متن کاملA New Method to Isolate and Culture Rat Kupffer Cells
BACKGROUND Previous methods for Kupffer cells (KCs) isolation require sophisticated skills and tedious procedures. Few studies have attempted to explore the self-renewal capacity of KCs in vitro. Therefore, the aim of this study was to establish a simple method for rat KCs isolation and further investigate the mitotic potential of KCs in vitro. METHODS KCs were obtained by performing one-step...
متن کاملMass isolation and culture of rat kupffer cells
Collagenase perfusion of the liver followed by pronase treatment of the cell suspension thus obtained gave a quantitative recovery of viable nonparenchymal liver cells (NPC). From these NPC, Kupffer (K) cells can be purified by attachment to tissue culture dishes. Tail vein injection of carbon 1-2 h before liver perfusion permitted stepwise calculation as well as visualization of carbon-contain...
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Ligand binding studies indicate that 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (AGEPC) down-regulates its own receptors on the plasma membrane of isolated rat Kupffer cells but has no significant effect on the binding affinity of the receptor for AGEPC. Exposure of isolated rat Kupffer cells to 10(-8) and 10(-6) M AGEPC resulted in a rapid, time-dependent reduction in the number of cell su...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1990
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.11.199